Yes, air duster is generally designed for use on electronics. There are a few things to watch out for: 1) avoid spraying the refrigerant liquid, which can happen if you shake the can, or angle it too much. The refrigerant is very cold, so can damage some sensitive electronics. 2) Avoid cheap retail dusters that contain bitterant. Many retail dusters have bitterant added to prevent huffing. When duster is used in the home, there is concern that the material will be purposely inhaled (called “huffing” or “dusting”) by minors, which can sometimes lead to tragic consequences. To avoid this, bitterant is added to make the duster taste bad. This same bitterant can lead to unwanted and potentially harmful residues on sensitive surfaces like electronic circuit boards.